Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

12-Hydroxymyricanone

12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM[1].

  • CAS Number: 191999-68-5
  • MF: C21H24O6
  • MW: 372.412
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 628.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 222.9±25.0 °C

L-Norvaline, N-[(2S)-6,8-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-, 1,1-dimethylethyl ester

L-Norvaline, N-[(2S)-6,8-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-, 1,1-dimethylethyl ester is a valine derivative[1].

  • CAS Number: 1309869-67-7
  • MF: C19H27F2NO2
  • MW: 339.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Suc-Ala-Ala-Ala-pNA

Suc-AAA-pNA?is the substrate of analysis of the reversible inhibition of porcine pancreatic elastase (PPE)[1].

  • CAS Number: 52299-14-6
  • MF: C19H25N5O8
  • MW: 451.43
  • Catalog: Others
  • Density: 1.37 g/cm3
  • Boiling Point: 923.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 512.3ºC

Formamide

Formamide is an amide derived from formic acid and has been used as solvent for many ionic compounds.

  • CAS Number: 75-12-7
  • MF: CH3NO
  • MW: 45.041
  • Catalog: Biochemical Assay Reagents
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 210.5±9.0 °C at 760 mmHg
  • Melting Point: 2-3 °C(lit.)
  • Flash Point: 81.1±18.7 °C

LNP Lipid-4

LNP Lipid-4 (Compound 8-8) is a lipid compound. LNP Lipid-4 is involved in the synthesis of lipid nanoparticles compositions. LNP Lipid-4 has potential applications in the transportation of biologically active substances[1].

  • CAS Number: 2795397-84-9
  • MF: C52H103NO9
  • MW: 886.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N4-Bz-5'-O-DMTr-3'-deoxy-3'-fluoro-beta-D-xylofuranosyl cytidine-2'-CED-phosphoramidite

N4-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-3’-deoxy-3’-fluoro-beta-D-xylofuranosyl cytidine-2’-CED-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

  • CAS Number: 1555759-30-2
  • MF: C46H51FN5O8P
  • MW: 851.90
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxy-2-pyridinemethanol

2-Hydroxymethyl-5-hydroxypyridine is isolated from the the matured, ripened and dried seeds of S. lychnophora.

  • CAS Number: 40222-77-3
  • MF: C6H7NO2
  • MW: 125.125
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 419.5±30.0 °C at 760 mmHg
  • Melting Point: 123-125ºC
  • Flash Point: 207.5±24.6 °C

1-Aminopropan-2-one hydrochloride

Aminoacetone hydrochloride is the simplest monopeptide. Aminoacetone hydrochloride is an intermediate in the metabolism of threonine and glycine. Aminoacetone hydrochloride is an endogenous substrate for semicarbazide-sensitive amine oxidase (SSAO), and can be used for determination of SSAO activity[1].

  • CAS Number: 7737-17-9
  • MF: C3H8ClNO
  • MW: 109.55
  • Catalog: Monoamine Oxidase
  • Density: 0.926g/cm3
  • Boiling Point: 120.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 26.8ºC

Boc-β-Lys(Z)-OH dicyclohexylammonium salt

Boc-β-Lys(Z)-OH (dicyclohexylammonium) salt is a lysine derivative[1].

  • CAS Number: 401792-89-0
  • MF: C31H51N3O6
  • MW: 561.75
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ATTO 680

ATTO 680 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 681/698 nm.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3’-Deoxy-3’-α-C-methyl-5-methyluridine

3’-Deoxy-3’-α-C-methyl-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 847650-50-4
  • MF: C11H16N2O5
  • MW: 256.26
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Manninotriose

Manninotriose is a novel and important player in the RFO(Raffinose family oligosaccharides) metabolism of red dead deadnettle; potential to improve the side effects of MTX for ALL treatment.

  • CAS Number: 13382-86-0
  • MF: C18H32O16
  • MW: 504.437
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 952.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 327.7±27.8 °C

Cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-

Chrysanthemic acid (NSC 11779) is an organic compound that is associated with a variety of natural and synthetic insecticides for the prevention of insect-borne diseases, among others[1].

  • CAS Number: 10453-89-1
  • MF: C10H16O2
  • MW: 168.23300
  • Catalog: Others
  • Density: 1.077g/cm3
  • Boiling Point: 246.4ºC at 760 mmHg
  • Melting Point: 50-51 °C
  • Flash Point: 119ºC

Cannabisin G

Cannabisin G is developed as a nutritional dietary supplement for immunocompromised individuals.

  • CAS Number: 163136-20-7
  • MF: C36H36N2O8
  • MW: 624.68
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5α-Cholesta-7,24-diene-3β-ol

5α-Cholesta-7,24-dien-3β-ol, a sterol, can be found in hamster cauda epididymal mature spermatozoa[1].

  • CAS Number: 651-54-7
  • MF: C27H44O
  • MW: 384.63800
  • Catalog: Others
  • Density: 1g/cm3
  • Boiling Point: 481.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 208.9ºC

Lopinavir-d8

(rel)-Lopinavir-d8 ((rel)-ABT-378-d8)is the deuterium labeledLopinavir(HY-14588)[1]. Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity[2][3]. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM[4].

  • CAS Number: 1322625-54-6
  • MF: C37H40D8N4O5
  • MW: 636.85
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 924.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 512.7±34.3 °C

N-Succinylglycine

N-Succinylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 5694-33-7
  • MF: C6H9NO5
  • MW: 175.13900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Acetoxy-1-methylquinolinium iodide

7-Acetoxy-1-methylquinolinium iodide (AMQI) is a fluorogenic substrate for cholinesterase (Ex = 320 nm, Em = 410 nm). Hydrolysis of 7-acetoxy-1-methylquinolinium iodide is used at the fluorometric flow system for the detection and identification of inhibitors.[1].

  • CAS Number: 7270-83-9
  • MF: C12H12INO2
  • MW: 329.13400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 222ºC(lit.)
  • Flash Point: N/A

MNG-14a

MNG-14a is an amphiphilic compound that can be used to aid the isolation of membrane proteins, and functional and structural determination of membrane proteins[1].

  • CAS Number: 1257853-50-1
  • MF: C145H144O36
  • MW: 2462.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Deruxtecan-d6

Deruxtecan-d6 is the deuterium labeled Dehydroepiandrosterone sulfate (sodium hydrate)[1].

  • CAS Number: 2760715-89-5
  • MF: C52H50D6FN9O13
  • MW: 1040.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-O-Cinnamoylglucose

1-O-trans-Cinnamoyl-β-D-glucopyranose is a nature product. 1-O-trans-Cinnamoyl-β-D-glucopyranose can be isolated from fruits[1].

  • CAS Number: 40004-96-4
  • MF: C15H18O7
  • MW: 310.29922
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Lys-Lys-Lys-Lys-OH AcOH

Tetralysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles[1].

  • CAS Number: 997-20-6
  • MF: C24H50N8O5
  • MW: 530.70400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ZINC 5,10,15,20-TETRA(4-PYRIDYL)-21 H,23 H-PORPHINE TETRAKIS(METHOCHLORIDE)

Zn(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 28850-44-4
  • MF: C44H36Cl4N8Zn
  • MW: 884.00
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >300ºC(lit.)
  • Flash Point: N/A

11-Hydroxyrankinidine

11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans[1].

  • CAS Number: 122590-03-8
  • MF: C20H24N2O4
  • MW: 356.42
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 550.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.9±32.9 °C

Isoarundinin II

Isoarundinin II is a stilbenoid compound[1].

  • CAS Number: 151538-56-6
  • MF: C22H22O4
  • MW: 350.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 trifluoroacetate salt

Mca-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(Dnp)-NH2 is a biological active peptide. (MMP substrate)

  • CAS Number: 158584-08-8
  • MF: C79H105N19O19S
  • MW: 1656.86
  • Catalog: MMP
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hexamethylphosphoramide-d18

Hexamethylphosphoramide-d18 is the deuterium labeled Hexamethylphosphoramide[1].

  • CAS Number: 51219-90-0
  • MF: C6H18N3OP
  • MW: 179.20000
  • Catalog: Others
  • Density: 1.032g/cm3
  • Boiling Point: 233ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 94.7ºC

(S)-2-AMINO-3-(CARBOXYFORMAMIDO)PROPANOIC ACID

(Rac)-Dencichin (2-Amino-3-(carboxyformamido)propanoic acid) is the racemate of Dencichin. Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity[1].

  • CAS Number: 7554-90-7
  • MF: C5H8N2O5
  • MW: 176.127
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH

Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide.

  • CAS Number: 908601-15-0
  • MF: C37H39N3O8
  • MW: 653.72100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Wnt/β-catenin agonist 2

Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction[1]. (From patent WO2007078113A1, compound 39)

  • CAS Number: 943820-93-7
  • MF: C13H12N4O3
  • MW: 272.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A