Curdione, one of the major sesquiterpene compounds from Rhizoma Curcumae, has been shown to exhibit multiple bioactive properties.IC50 value: 60–80 μMTarget:In vitro: The study of the influence of curdione on the hemorheological changes in blood stasis model rats and thrombolysis in vitro showed that curdione only possessed thrombolytic effect in dose of 0.235 g·L-1 and 2.35 g·L-1, but has not the notable activity of thrombolysis [1]. The effects of curdione on human platelet aggregation induced by thrombin (0.3 U/ml) were tested in vitro. Curdione preferentially inhibited PAF- and thrombin- induced platelet aggregation in a concentration-dependent manner (IC50: 60–80 μM), whereas much higher concentrations of curdione were required to inhibit platelet aggregation induced by ADP and AA. Curdione also inhibited P-selectin expression in PAF-activated platelets. Moreover, curdione caused an increase in cAMP levels and attenuated intracellular Ca2+ mobilization in PAF-activated platelets. In vivo: Curdione showed significant antithrombotic activity [2].
Chromium(III) (acetate) (Chromic acetate) is an ionic crosslinker[1].
DL-Glutamic acid-d5 is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability[1].
6′-O-β-D-Glucopyranosylphlorigidoside C (compound 1) is an iridoid glycoside that can be isolated from Lamiophlomis rotata[1].
5,8-Dihydroxy-6,7-dimethoxyflavone, isolated from aerial parts of Gnaphalium gaudichaudianum, has antitumor activity[1].
Calycanthoside is a natural compound isolated from Angelica tenuissima[1].
Deacetyldiltiazem-d6 (hydrochloride) is the deuterium labeled Deacetyldiltiazem hydrochloride[1].
Pd(II)TMPyP tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation[1].
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(o-tolyl)propanoic acid is a phenylalanine derivative[1].
Hexadecyl palmitate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
1-Furfurylpyrrole has been identified as a potential contributor of flavor and aroma to popcorn.
Nitrofurantoin-13C3is the 13C labeledNitrofurantoin(HY-A0090)[1]. Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[2].
3’-beta-C-Methylcytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability[1][2].
2,5-Hexanedione-d10 is the deuterium labeled 2,5-Hexanedione[1].
5-Methyl-2-thiouridine (2-Thio-5-methyluridine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
DL-Cystine is a cysteine derivative[1].
22:0 Lyso PC-13C6 is a 13C-labeled and deuterium labeled 22:0 Lyso PC[1].
Carmichasine B is a natural diterpenoid Alkaloid that can be isolated from Aconitum carmichaelii[1].
Gosferol is a furocoumarin from the roots of Prangos ferulacea[1].
Hosenkoside N is a baccharane glycoside isolated from lmpatiens buhamina[1].
2-(3-Hydroxy-2-oxoindolin-3-yl)-acetic acid (compound 29) is a natural polyphenol compound found in hop bract[1].
D-Erythrose-d2 is the deuterium labeled D-Erythrose[1].
Benzyl salicylate is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber.
Boc-Arg(di-Z)-OH can be used for the synthesis of amino acid. Boc-Arg(di-Z)-OH can be used for the research of inhibitors for processing proteinases. Boc-Arg(di-Z)-OH is coupled via the mixed anhydride (MA) with HGlu(OBzl)-Lys(Z)-Arg(Z,Z)-CH2Cl[1].
Fmoc-D-HoPhe-OH is a phenylalanine derivative[1].
α-Synuclein (32-37) (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
IGF1Rtide can be used as a RET kinase substrate for RET kinase assays[1].
β-Obscurine is a lycopodine-type alkaloid, which can be isolated from the club moss Lycopodium casuarinoides[1].