Cyclocephaloside II is a natural product that can be obtained from the roots of Astragalus brachypterus and Astragalus microcephalus[1].
Nodakenetin-Glucose-malonic acid is a natural compound[1].
Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-AMC (Renin Substrate I) is a renin substrate[1]
Biotin-PEG3-CONH-Ph-CF3-diazirine is a biotin labeled PEG3 derivative. Biotin-PEG3-CONH-Ph-CF3-diazirine can be used for protein labeling[1].
Magenta-β-D-GlcA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
(±)-Ractopamine-d6 Ketone HCl (1-methyl-d3-propyl-1,2,2-d3) is the deuterium labeled (±)-Ractopamine-d6 Ketone HCl[1].
3-(Bromomethyl)-2-methylpentane-d7 is the deuterium labeled 3-(Bromomethyl)-2-methylpentane[1].
Trehalose 6,6′-dimycolate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Bone-1064 is a EuK-based PSMA tetramer bone probe for high-contrast visualization of bone in surrounding tissue. Bone-1064 specifically binds hydroxyapatite in bone tissue and can be used for NIR-II fluorescence imaging in animal models[1].
Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells[1][2].
WAY-658675 is an active molecule.
Lithocholic acid-d5 is deuterium labeled Lithocholic acid.
Clovamide (trans-Clovamide), a natural phenolic compound, is a potent antioxidant. Clovamide is an excellent ROS and oxygen radical scavenger. Clovamide also has anti-inflammatory and neuroprotective effects[1][2]. Clovamide is an anti-microbial with activity against the human pathogens influenza A subtype H5N1, Trypanosoma evansi, and Heliobacter pylori[3].
CDK4/6-IN-10 is a potent, selective and orally active CDK4 and CDK6 inhibitor with IC50s of 22 nM and 10 nM, respectively. CDK4/6-IN-10 shows antitumor activity. CDK4/6-IN-10 has the potential for the research of Multiple myeloma (MM)[1].
[1-13Cglc]Lactose monohydrate is an isotopic labeling drug[1].
Yuanamide is an alkaloid that can be isolated from Corydalis[1].
Poriferasterol is a sterol that can be isolated from sponges[1].
(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH is a biologically active peptide.
Ala-Ala-Gln is a peptide. Ala-Ala-Gln can be used for various biochemical studies[1].
Calpain-1 substrate, fluorogenic serves as a sensitive and specific substrate for calpain-1 that cleaves Tyr-Gly bond and results in enhanced fluorescence[1].(Ex/Em = 490 nm/518 nm)
D-Ala-Ala is a peptide.
PEG 18 cetostearyl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is a potent, selective, ATP competitive CHK1 and CHK2 inhibitor, with a Ki of 0.9 nM for CHK1 and IC50s of <1 nM, 8 nM for CHK1 and CHK2, respectively. Prexasertib Mesylate Hydrate inhibits HT-29 CHK1 autophosphorylation (S296) and HT-29 CHK2 autophosphorylation (S516). Prexasertib Mesylate Hydrate shows potent anti-tumor activity, significantly abrogates the G2/M checkpoint in p53 deficient HeLa cells with an EC50 of 9 nM[1].
Pectic acid (Methyl protopectin), a polygalacturonic acid, induces cell apoptosis and necrosis in pituitary tumor cells. Pectic acid can be used in the research of cancers and autoimmune disease[2][3].
Stigmast-4-ene-3β,6β-diol is a stigmasterol, that can be isolated from Nux Prinsepiae[1].
N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)-d24 is the deuterium labeled N1,N1'-(Propane-1,3-diyl)bis(propane-1,3-diamine)[1].
7-Acetoxy-4-methylcoumarin is an inhibitor of GST.7-Acetoxy-4-methylcoumarin inhibits AFB1-DNA binding in vitro with 36.7% inhibition[1][2].
3-Pyridylacetic acid-d4 (hydrochloride) is the deuterium labeled 3-Pyridylacetic acid hydrochloride[1]. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids)[2][3].
Cnidioside B methyl ester is a glucoside compound，which can be isolated from Ami mjus L[1].