1,2,4-Triazin-3-amine

Modify Date: 2024-01-02 06:31:25

1,2,4-Triazin-3-amine Structure
1,2,4-Triazin-3-amine structure
Common Name 1,2,4-Triazin-3-amine
CAS Number 1120-99-6 Molecular Weight 96.09070
Density 1.346g/cm3 Boiling Point 311.7ºC at 760mmHg
Molecular Formula C3H4N4 Melting Point 174-177 °C(lit.)
MSDS N/A Flash Point 168ºC

 Use of 1,2,4-Triazin-3-amine


3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion[1].

 Names

Name 3-Amino-1,2,4-triazine
Synonym More Synonyms

 1,2,4-Triazin-3-amine Biological Activity

Description 3-Amino-1,2,4-triazine is an inhibitor of NO synthase, and also inhibits nitrite secretion[1].
Related Catalog
In Vitro 3-Amino-1,2,4-triazine (50 mM; 7 h) inhibits NO synthase activity in cytosolic extracts of activated cells[1]. 3-Amino-1,2,4-triazine (5-50 mM; 24 h) inhibits both nitrite secretion and parasite killing by activated macrophages[1].

 Chemical & Physical Properties

Density 1.346g/cm3
Boiling Point 311.7ºC at 760mmHg
Melting Point 174-177 °C(lit.)
Molecular Formula C3H4N4
Molecular Weight 96.09070
Flash Point 168ºC
Exact Mass 96.04360
PSA 64.69000
LogP 0.03500
Vapour Pressure 0.000553mmHg at 25°C
Index of Refraction 1.61

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XY2969000
CHEMICAL NAME :
as-Triazine, 3-amino-
CAS REGISTRY NUMBER :
1120-99-6
LAST UPDATED :
199309
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H4-N4
MOLECULAR WEIGHT :
96.11
WISWESSER LINE NOTATION :
T6NN DNJ CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 95,123,1953

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
WGK Germany 3
RTECS XY2969000
HS Code 2933699090

 Synthetic Route

~90%

1,2,4-Triazin-3-amine Structure

1,2,4-Triazin-3...

CAS#:1120-99-6

Literature: Weng, Lingkai; Qiao, Lei; Zhou, Jiacheng; Liu, Pingli; Pan, Yongchun Patent: US2009/291956 A1, 2009 ; Location in patent: Page/Page column 25-26 ;

~85%

1,2,4-Triazin-3-amine Structure

1,2,4-Triazin-3...

CAS#:1120-99-6

Literature: Glomb; Tschirnich Journal of Agricultural and Food Chemistry, 2001 , vol. 49, # 11 p. 5543 - 5550

~%

1,2,4-Triazin-3-amine Structure

1,2,4-Triazin-3...

CAS#:1120-99-6

Literature: Journal of the American Chemical Society, , vol. 74, p. 4706

 Customs

HS Code 2933699090
Summary 2933699090 other compounds containing an unfused triazine ring (whether or not hydrogenated) in the structure。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%

 Synonyms

1,2,4]TRIAZIN-3-YLAMINE
3-Amino-1,2,4-Triazine
3-AMINO-1 2 4-TRIAZINE
EINECS 214-324-7
1,2,4-TRIAZINE-3-AMINE
1,2,4-Triazin-3-amine
1,2,4-TRIAZIN-3-AMIN
MFCD00006459
1,2,4-triazine-3-ylamine