Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Nicotredole

Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity[1][2][3].

  • CAS Number: 29876-14-0
  • MF: C16H15N3O
  • MW: 265.310
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 588.4±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 309.7±25.9 °C

Monomethyl auristatin E intermediate-11

Monomethyl auristatin E intermediate-11 is an intermediate reactant in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

  • CAS Number: 870640-62-3
  • MF: C14H23NO
  • MW: 221.33852
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Fluorobenzoylchloride

4-Fluorobenzoyl-2,3,5,6-d4 chloride is the deuterium labeled 4-Fluorobenzoyl chloride[1].

  • CAS Number: 1071809-52-3
  • MF: C7ClD4FO
  • MW: 158.557
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 180.6±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 82.2±0.0 °C

1-Bromodecane-d4

1-Bromodecane-d4 is the deuterium labeled 1-Bromodecane[1].

  • CAS Number: 1219805-58-9
  • MF: C10H21Br
  • MW: 221.178
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 241.0±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 94.4±0.0 °C

Vanutide cridificar

Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate. Vanutide cridificar can be used for Alzheimer's disease (AD) research[1].

  • CAS Number: 886584-10-7
  • MF:
  • MW:
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MGL-3196

MGL-3196 is a highly selective thyroid hormone receptor β (THR-β) agonist with an EC50 value of 0.21 μM.

  • CAS Number: 920509-32-6
  • MF: C17H12Cl2N6O4
  • MW: 435.22100
  • Catalog: Cardiovascular Disease
  • Density: 1.65±0.1 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Palazestrant

Palazestrant is an antiestrogen and antineoplastic agent. Palazestrant in combination with a HER2 inhibitor, works on ER+/HER2+ cancer[1][2].

  • CAS Number: 2092925-89-6
  • MF: C28H36FN3O
  • MW: 449.60
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BCIP

BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

  • CAS Number: 6578-06-9
  • MF: C15H15BrClN2O4P
  • MW: 433.621
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: 580.2ºC at 760 mmHg
  • Melting Point: 194-195ºC
  • Flash Point: 304.7ºC

Fluorothyl

Fluorothyl (Flurothyl) is a inhaling volatile liquid.

  • CAS Number: 333-36-8
  • MF: C4H4F6O
  • MW: 182.06400
  • Catalog: Others
  • Density: 1.404 g/mL at 25 °C(lit.)
  • Boiling Point: 62-63 °C(lit.)
  • Melting Point: N/A
  • Flash Point: 35 °F

2-methoxy-N,N,beta-trimethyl-10H-phenothiazine-10-propylamine

(±)-Levomepromazine is the racemate of Levomepromazine. Levomepromazine is an orally active and potent antipsychotic agent[1].

  • CAS Number: 851-68-3
  • MF: C19H24N2OS
  • MW: 328.47200
  • Catalog: Neurological Disease
  • Density: 1.125g/cm3
  • Boiling Point: 468ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 236.8ºC

1,4,5-Trihydroxy-9H-xanthen-9-one

Subelliptenone G is a simple oxygenated xanthone that can be isolated from the root bark of Garcinia subelliptica[1].

  • CAS Number: 162473-22-5
  • MF: C13H8O5
  • MW: 244.20
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 490.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.9±22.2 °C

Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067[1].

  • CAS Number: 2264011-98-3
  • MF: C33H35N5O9
  • MW: 645.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sitoindoside I

Sitoindoside I (Longiside B; Sitoindoside; Daucosterol 6'-O-palmitate) is a compound that can be isolated from Gyn'nops walla Gaertn[1].

  • CAS Number: 18749-71-8
  • MF: C51H90O7
  • MW: 815.256
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 811.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.0±27.8 °C

Thiamine nitrate

Thiamine nitrate is an essential vitamin which can enhance normal neuronal actives.

  • CAS Number: 532-43-4
  • MF: C12H17N5O4S
  • MW: 327.359
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 196-200°C
  • Flash Point: N/A

Ganglioside sialidase (AuSialidase M2)

Ganglioside sialidase (AuSialidase M2) from Arthrobacter ureafaciens. Ganglioside sialidase is a highly specific N-acetylneuraminidase. Ganglioside sialidase can hydrolyze the internal sialic acid of GM1 under optimal condition with sodium cholate[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Adipate-13C6 sodium

Adipate-13C6 (sodium) is the 13C labeled Sodium adipate[1].

  • CAS Number: 2483735-36-8
  • MF: 13C6H8Na2O4
  • MW: 196.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Physcion

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively[1][2]. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[2].

  • CAS Number: 521-61-9
  • MF: C16H12O5
  • MW: 284.26
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 560.5±50.0 °C at 760 mmHg
  • Melting Point: 196-206°C
  • Flash Point: 215.4±23.6 °C

KRN2

KRN2 is a selective inhibitor of nuclear factor of activated T cells (NFAT5), with an IC50 of 0.1 μM.

  • CAS Number: 248260-75-5
  • MF: C27H23ClFNO4
  • MW: 479.93
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-AMINO-1,3-NAPHTHALENEDISULFONIC ACID MONOPOTASSIUM SALT

2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc[1].

  • CAS Number: 842-15-9
  • MF: C10H8KNO6S2
  • MW: 341.40200
  • Catalog: Inflammation/Immunology
  • Density: 0.881 g/mL at 25 °C(lit.)
  • Boiling Point: 159-161 °C(lit.)
  • Melting Point: −69 °C(lit.)
  • Flash Point: 107 °F

H-Gly-Arg-OH

H-Gly-Arg-OH is adipeptide.

  • CAS Number: 18635-55-7
  • MF: C8H17N5O3
  • MW: 231.25
  • Catalog: Others
  • Density: 1.51g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5',5-Difluoro BAPTA tetrapotassium

5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube[1][2].

  • CAS Number: 152290-47-6
  • MF: C22H18F2N2O10.4K
  • MW: 664.7757264
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dihydroseselin

Dihydroseselin is a 7-hydroxycoumarin (HY-N0573) derivative. 7-hydroxycoumarin is a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent[1]

  • CAS Number: 2221-66-1
  • MF: C14H14O3
  • MW: 230.25900
  • Catalog: Others
  • Density: 1.190±0.06 g/cm3(Predicted)
  • Boiling Point: 387.3±42.0 °C(Predicted)
  • Melting Point: 104-105 °C
  • Flash Point: N/A

pTH (1-31) amide (human)

Human PTH-(1-31) amide is a PTH analog. Human PTH-(1-31) amide stimulate phosphatidylcholine hydrolysis and stimulates adenylyl cyclase release[1].

  • CAS Number: 173833-08-4
  • MF: C162H270N50O46S2
  • MW:
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mildronate

Mildronate (Meldonium) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1].

  • CAS Number: 76144-81-5
  • MF: C6H14N2O2
  • MW: 146.188
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 85-90ºC
  • Flash Point: N/A

Aflatoxin G1

Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].

  • CAS Number: 1165-39-5
  • MF: C17H12O7
  • MW: 328.273
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 612.1±55.0 °C at 760 mmHg
  • Melting Point: 244-246ºC
  • Flash Point: 274.1±31.5 °C

RS-246204

RS-246204 is a R-spondin-1 substitute compound that is able initiate small intestinal organoids without the use of the R-spondin-1 protein.

  • CAS Number: 878451-87-7
  • MF: C16H13N5O2S
  • MW: 339.372
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ppicolinic-3,4,5,6-d4 acid

Ppicolinic-3,4,5,6-d4 acid is the deuterium labeled Ppicolinic acid[1].

  • CAS Number: 284487-61-2
  • MF: C6HD4NO2
  • MW: 127.13400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Nitro(2H9)fluoranthene

3-Nitrofluoranthene-d9 is the deuterium labeled 3-Nitrofluoranthene[1].

  • CAS Number: 350820-11-0
  • MF: C16D9NO2
  • MW: 256.304
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 445.5±14.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 223.5±12.9 °C

CS476

CS476 is a potent hypoglycaemic agent.

  • CAS Number: 41177-35-9
  • MF: C24H29N3O5S
  • MW: 471.56900
  • Catalog: Cardiovascular Disease
  • Density: 1.35g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fluometuron-d6

Fluometuron-d6 is the deuterium labeled 4-Nitrobenzaldehyde[1].

  • CAS Number: 2030182-29-5
  • MF: C10H5D6F3N2O
  • MW: 238.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A