Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

LYCBX

LYCBX is a neuronal tracer, a fluorescent biotin derivative of Lucifer Yellow[1].

  • CAS Number: 223914-41-8
  • MF: C33H42K2N6O11S3
  • MW: 873.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Suc-Ala-Phe-Lys-AMC

Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K[1][2].

  • CAS Number: 73207-91-7
  • MF: C32H39N5O8
  • MW: 621.68100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one

7-Hydroxy-3-(4-hydroxybenzylidene)chroman-4-one, a homoisoflavonoid, can be isolated from the dried heartwood of Caesalpinia sappan[1].

  • CAS Number: 110064-50-1
  • MF: C16H12O4
  • MW: 268.26
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 547.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.5±23.6 °C

ML-290

ML-290 is a potent and orally active relaxin/insulin-like family peptide receptor (RXFP1) agonist and activator of anti-fibrotic genes, with an EC50 of 94 nM[1].

  • CAS Number: 1482500-76-4
  • MF: C24H21F3N2O5S
  • MW: 506.49
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 523.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 270.4±30.1 °C

n-2-nitrophenylsulfenyl-l-alanine dicyclohexylammonium salt

N-2-Nitrophenylsulfenyl-L-alanine Dicyclohexylammonium Salt is an alanine derivative[1].

  • CAS Number: 7675-46-9
  • MF: C21H33N3O4S
  • MW: 423.56900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 593.5ºC at 760 mmHg
  • Melting Point: 176ºC
  • Flash Point: 312.7ºC

RdRP-IN-3

RdRP-IN-3 is a promising anti-influenza drug candidate by inhibiting the activity of RNA-dependent RNA polymerase (RdRp).

  • CAS Number: 2641299-75-2
  • MF: C25H21N3O4
  • MW: 427.45
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Salirepin

Salirepin is a phenolic glycoside from fruits of Idesia polycarpa, inhibits LPS-induced nitric oxide production[1].

  • CAS Number: 26652-12-0
  • MF: C13H18O8
  • MW: 302.28
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 633.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 336.8±31.5 °C

Amyloid β-Protein (1-6) amide trifluoroacetate salt

Q-Peptide is the angiopoietin-1 derived peptide (QHREDGS).Q-Peptide increases keratinocyte migration to improve wound healing, in diabetic mouse model. Q-Peptide accelerates wound closure[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

clofedanol

Chlophedianol is an orally active and potent antitussive agent. Chlophedianol can be used for the research of acute cough due to upper respiratory tract infections (URIs)[1][2].

  • CAS Number: 791-35-5
  • MF: C17H20ClNO
  • MW: 289.80000
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 120°
  • Flash Point: N/A

Damulin A

Damulin A is a saponin found in G. pentaphyllum with anti-cancer activities[1].

  • CAS Number: 1202868-74-3
  • MF: C42H70O13
  • MW: 783.00
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Phe(3,5-DiF)-OH

Fmoc-Phe(3,5-DiF)-OH is a phenylalanine derivative[1].

  • CAS Number: 205526-24-5
  • MF: C24H19F2NO4
  • MW: 423.409
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 610.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323.1±31.5 °C

Streptolysin O

Streptolysin O, a group A streptococcal toxin, is a well-characterized oxygen-labile prototype of a cholesterol-binding bacterial exotoxin. Streptolysin O causes both lysis of cells and cardiotoxicity. Streptolysin O is widely used for the controlled permeabilization of cell membranes. Streptolysin O exists in two forms, a reduced active state and an oxidized reversibly inactive state [1][2][3][4].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Glu-Glu-βNA

Glu-Glu-βNA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

  • CAS Number: 23645-15-0
  • MF: C20H23N3O6
  • MW: 401.41
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 843.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 464.0±34.3 °C

YYRADDA

YYRADDA is a polypeptide. YYRADDA stimulates the growth of collagen in the extracellular matrix of the skin. YYRADDA improves the appearance of the skin and promotes the healing of damaged skin[1].

  • CAS Number: 1082226-36-5
  • MF: C34H47N9O11
  • MW: 757.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4'-O-Glucosylvitexin

Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta[1].

  • CAS Number: 38950-94-6
  • MF: C27H30O15
  • MW: 594.51800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ac9-25 TFA

Ac9-25, a N-terminal peptide of Annexin I, acts as a formyl peptide receptor (FPR) agonist and activates the neutrophil NADPH oxidase through FPR[1][2].

  • CAS Number: 284040-76-2
  • MF: C99H143N23O33
  • MW: 320.38700
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(2-Thienylsulfonyl)leucine

N-(2-Thienylsulfonyl)leucine is a leucine derivative[1].

  • CAS Number: 82068-15-3
  • MF: C10H15NO4S2
  • MW: 277.36
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Iodo-2',3'-dideoxy-7-deazaadenosine

7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions[1].

  • CAS Number: 114748-70-8
  • MF: C11H13IN4O2
  • MW: 360.151
  • Catalog: Others
  • Density: 2.2±0.1 g/cm3
  • Boiling Point: 579.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.2±30.1 °C

Boc-L-phenylalanine methyl ester

N-Boc-L-phenylalanine methyl ester is a phenylalanine derivative[1].

  • CAS Number: 51987-73-6
  • MF: C15H21NO4
  • MW: 279.332
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 403.8±38.0 °C at 760 mmHg
  • Melting Point: 36-40 °C(lit.)
  • Flash Point: 198.0±26.8 °C

β-Amyloid (1-40), FAM-labeled

β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm)[1].

  • CAS Number: 1678416-08-4
  • MF: C20H21N3OS
  • MW: 351.465
  • Catalog: Neurological Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 599.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 316.5±30.1 °C

2,3,2",3"-Tetrahydroochnaflavone

2,3,2'',3''-Tetrahydroochnaflavone is a biflavonoid, which can be isolated from the leaves of Quintinia acutifolia. 2,3,2'',3''-Tetrahydroochnaflavone shows some cytotoxicity against P388 murine lymphocytic leukemia cells, with an IC50 of 8.2 µg/mL[1].

  • CAS Number: 678138-59-5
  • MF: C30H22O10
  • MW: 542.490
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 852.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 287.0±27.8 °C

Carzenide

Carzenide is an organic synthesis intermediate, for synthetic drug.

  • CAS Number: 138-41-0
  • MF: C7H7NO4S
  • MW: 201.200
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 449.0±47.0 °C at 760 mmHg
  • Melting Point: 285-295 °C(lit.)
  • Flash Point: 225.4±29.3 °C

1-Hexanol-d3

1-Hexanol-d3 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].

  • CAS Number: 52598-04-6
  • MF: C6H12D2O
  • MW: 104.18700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 21586-90-3
  • MF: C20H28O9
  • MW: 412.43
  • Catalog: Others
  • Density: 1.60±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 262-263 ºC
  • Flash Point: N/A

Daclatasvir Impurity B

Daclatasvir Impurity B is the impurity of Daclatasvir. Daclatasvir is a potent HCV NS5A protein inhibitor[1].

  • CAS Number: 2226541-13-3
  • MF: C35H41N7O4
  • MW: 623.74
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

KRAS inhibitor-4

KRAS inhibitor-4 (compound F12) is a potent KRAS inhibitor and developed as anticancer agents[1].

  • CAS Number: 2374152-69-7
  • MF: C30H39ClN8O
  • MW: 563.14
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Shz 1

Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells[1].

  • CAS Number: 326886-05-9
  • MF: C13H11BrN2O3S
  • MW: 355.207
  • Catalog: Cardiovascular Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 503.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.5±32.9 °C

Coppersensor 1

Coppersensor-1 (CS1) is a boron dipyrromethene (BODIPY)-based fluorescent sensor for selective and sensitive detection of copper(I) ions (Cu+) in biological samples, including live cells[1].

  • CAS Number: 874748-20-6
  • MF: C30H50BF2N3S4
  • MW: 629.81
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DAF-2

4,5-Diaminofluorescein is a fluorescent detector for nitric oxide (NO) in cells and tissues[1].

  • CAS Number: 205391-01-1
  • MF: C20H14N2O5
  • MW: 362.336
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 760.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 413.9±32.9 °C

5-Fluorocytidine

5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor[1].

  • CAS Number: 2341-22-2
  • MF: C9H12FN3O5
  • MW: 261.207
  • Catalog: Others
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 511.4±60.0 °C at 760 mmHg
  • Melting Point: 196-200 °C(lit.)
  • Flash Point: 263.1±32.9 °C