Azido-PEG1-azide
Modify Date: 2024-01-15 08:19:55
Azido-PEG1-azide structure
|
Common Name | Azido-PEG1-azide | ||
|---|---|---|---|---|
| CAS Number | 24345-74-2 | Molecular Weight | 156.14600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C4H8N6O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Azido-PEG1-azideAzido-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | 1-azido-2-(2-azidoethoxy)ethane |
|---|---|
| Synonym | More Synonyms |
| Description | Azido-PEG1-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C4H8N6O |
|---|---|
| Molecular Weight | 156.14600 |
| Exact Mass | 156.07600 |
| PSA | 108.73000 |
| LogP | 0.52912 |
| HS Code | 2929909090 |
|---|
|
~95%
Azido-PEG1-azide CAS#:24345-74-2 |
| Literature: Thomas, Jason R.; Liu, Xianjun; Hergenrother, Paul J. Journal of the American Chemical Society, 2005 , vol. 127, # 36 p. 12434 - 12435 |
|
~62%
Azido-PEG1-azide CAS#:24345-74-2 |
| Literature: Vereshchagin, L. I.; Tikhonova, L. G.; Maksikova, A. V.; Serebryakova, E. S.; Proidakov, A. G.; Filippova, T. M. Journal of Organic Chemistry USSR (English Translation), 1980 , vol. 16, # 4 p. 641 - 648 Zhurnal Organicheskoi Khimii, 1980 , vol. 16, # 4 p. 730 - 738 |
|
~%
Azido-PEG1-azide CAS#:24345-74-2 |
| Literature: WO2011/25790 A1, ; Page/Page column 50 ; |
CAS#:2752-17-2| HS Code | 2929909090 |
|---|---|
| Summary | 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
| bisethyletherazide |
| 1-azido-2 (2-azidoethoxy)-ethane |
| 1-(2-azidoethoxy)-2-azidoethane |
| Ether,bis(2-azidoethyl) (7CI,8CI) |
| 1,1'-Oxybis(2-azidoethane) |
| Ethane,1,1'-oxybis[2-azido |
| 1,5-diazido-3-oxapentane |
| bis-(2-azido-ethyl) ether |