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1480545-09-2

1480545-09-2 structure
1480545-09-2 structure
  • Name: Azido-PEG1-CH2CO2-NHS
  • Chemical Name: Azido-PEG1-CH2CO2-NHS
  • CAS Number: 1480545-09-2
  • Molecular Formula: C8H10N4O5
  • Molecular Weight: 242.19
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 16:02:06
  • Modify Date: 2024-04-03 11:47:11
  • Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Azido-PEG1-CH2CO2-NHS
Description Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H10N4O5
Molecular Weight 242.19
Hazard Codes Xi