Azido-PEG1-CH2CO2-NHS

Modify Date: 2024-04-03 11:47:11

Azido-PEG1-CH2CO2-NHS Structure
Azido-PEG1-CH2CO2-NHS structure
Common Name Azido-PEG1-CH2CO2-NHS
CAS Number 1480545-09-2 Molecular Weight 242.19
Density N/A Boiling Point N/A
Molecular Formula C8H10N4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG1-CH2CO2-NHS


Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG1-CH2CO2-NHS

 Azido-PEG1-CH2CO2-NHS Biological Activity

Description Azido-PEG1-CH2CO2-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H10N4O5
Molecular Weight 242.19

 Safety Information

Hazard Codes Xi