Azido-PEG8-CH2CO2-NHS

Modify Date: 2024-01-11 08:11:44

Azido-PEG8-CH2CO2-NHS Structure
Azido-PEG8-CH2CO2-NHS structure
Common Name Azido-PEG8-CH2CO2-NHS
CAS Number 2182601-81-4 Molecular Weight 550.56
Density N/A Boiling Point N/A
Molecular Formula C22H38N4O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG8-CH2CO2-NHS


Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG8-C1-NHS ester

 Azido-PEG8-CH2CO2-NHS Biological Activity

Description Azido-PEG8-C1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H38N4O12
Molecular Weight 550.56