Bis(2-bromoethyl) ether structure
|
Common Name | Bis(2-bromoethyl) ether | ||
---|---|---|---|---|
CAS Number | 5414-19-7 | Molecular Weight | 231.914 | |
Density | 1.8±0.1 g/cm3 | Boiling Point | 216.3±0.0 °C at 760 mmHg | |
Molecular Formula | C4H8Br2O | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 85.0±0.0 °C | |
Symbol |
GHS05, GHS07 |
Signal Word | Danger |
Use of Bis(2-bromoethyl) etherBis2-bromoethyl ether is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
Name | 2,2'-Dibromodiethyl ether |
---|---|
Synonym | More Synonyms |
Description | Bis2-bromoethyl ether is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
Alkyl-Chain |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.8±0.1 g/cm3 |
---|---|
Boiling Point | 216.3±0.0 °C at 760 mmHg |
Molecular Formula | C4H8Br2O |
Molecular Weight | 231.914 |
Flash Point | 85.0±0.0 °C |
Exact Mass | 229.894180 |
PSA | 9.23000 |
LogP | 1.87 |
Vapour Pressure | 0.2±0.4 mmHg at 25°C |
Index of Refraction | 1.506 |
Storage condition | 2-8°C |
Symbol |
GHS05, GHS07 |
---|---|
Signal Word | Danger |
Hazard Statements | H315-H318-H335 |
Precautionary Statements | P261-P280-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
Hazard Codes | T:Toxic; |
Risk Phrases | R61;R37/38;R41 |
Safety Phrases | S53-S26-S36/37/39-S45 |
RIDADR | 2810 |
WGK Germany | 3 |
Packaging Group | III |
Hazard Class | 6.1 |
HS Code | 2909199090 |
HS Code | 2909199090 |
---|---|
Summary | 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
Asymmetric synthesis of functionalized diarylmethanols catalyzed by a new gamma-amino thiol.
J. Org. Chem. 71(2) , 833-5, (2006) [reaction: see text] A mild asymmetric arylation of aromatic aldehydes catalyzed by gamma-amino thiol 5 gave the corresponding diarylmethanols with 95 to >99.5% ee. |
|
J. Chem. Soc. Chem. Commun. , 1550, (1992)
|
|
J. Chem. Soc., Perkin Trans. II , 1213, (1989)
|
MFCD00039196 |
1-Bromo-2-(2-bromoethoxy)ethane |
2-Bromoethyl ether |
2,2-Dibromodiethyl Ether |
Ethane, 2,2'-oxybis[1-bromo- |
2,2'-Dibromodiethyl Ether |
2,2'-Dibromoethylether |
Ether, bis(2-bromoethyl) |
Ether, bis(2-bromoethyl) (8CI) |
Ethane, 1,1'-oxybis[2-bromo- |
Bis(2-bromoethyl) ether |
DI(2-BROMOETHYL)ETHER |
EINECS 226-504-2 |