MCHr1 antagonist 1
Modify Date: 2025-08-26 16:56:04
MCHr1 antagonist 1 structure
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Common Name | MCHr1 antagonist 1 | ||
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| CAS Number | 391610-37-0 | Molecular Weight | 557.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H33F2N5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MCHr1 antagonist 1MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass. |
| Name | MCHr1 antagonist 1 |
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| Description | MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass. |
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| Related Catalog | |
| Target |
Kb: 1 nM (Human MCH1)[1] Ki: 4 nM (Human MCH1)[1] |
| In Vitro | MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1]. |
| References |
| Molecular Formula | C28H33F2N5O5 |
|---|---|
| Molecular Weight | 557.59 |
| InChIKey | FFXFCSQUTLDLAR-UHFFFAOYSA-N |
| SMILES | COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(c3ccccn3)CC2)C(=O)N1 |