PAC1R antagonist 1

Modify Date: 2025-08-25 18:11:18

PAC1R antagonist 1 Structure
PAC1R antagonist 1 structure
Common Name PAC1R antagonist 1
CAS Number 2305204-24-2 Molecular Weight 372.81
Density N/A Boiling Point N/A
Molecular Formula C17H17ClN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PAC1R antagonist 1


PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].

 Names

Name PAC1R antagonist 1

 PAC1R antagonist 1 Biological Activity

Description PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].
Related Catalog
References

[1]. Takasaki I, et, al. Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain. Eur J Med Chem. 2020 Jan 15;186:111902.

 Chemical & Physical Properties

Molecular Formula C17H17ClN6O2
Molecular Weight 372.81
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