A3AR antagonist 1

Modify Date: 2024-01-07 13:02:54

A3AR antagonist 1 Structure
A3AR antagonist 1 structure
Common Name A3AR antagonist 1
CAS Number 2413257-74-4 Molecular Weight 560.62
Density N/A Boiling Point N/A
Molecular Formula C32H24N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of A3AR antagonist 1


A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].

 Names

Name A3AR antagonist 1

 A3AR antagonist 1 Biological Activity

Description A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].
Related Catalog
Target

hA3:4.63 nM (Ki)

References

[1]. Abdelrahman A, et, al. Substituted 4-phenylthiazoles: Development of potent and selective A 1, A 3 and dual A 1/A 3 adenosine receptor antagonists. Eur J Med Chem. 2020 Jan 15;186:111879.

 Chemical & Physical Properties

Molecular Formula C32H24N4O4S
Molecular Weight 560.62
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