2413257-74-4

2413257-74-4 structure

Name: A3AR antagonist 1
Chemical Name: A3AR antagonist 1
CAS Number: 2413257-74-4
Molecular Formula: C₃₂H₂₄N₄O₄S
Molecular Weight: 560.62
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2022-07-13 15:56:56
Modify Date: 2025-10-14 01:37:31
A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].

Name	A3AR antagonist 1

Description	A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	hA3:4.63 nM (Ki)
References	[1]. Abdelrahman A, et, al. Substituted 4-phenylthiazoles: Development of potent and selective A 1, A 3 and dual A 1/A 3 adenosine receptor antagonists. Eur J Med Chem. 2020 Jan 15;186:111879.

Molecular Formula	C₃₂H₂₄N₄O₄S
Molecular Weight	560.62