2305204-24-2

2305204-24-2 structure

Name: PAC1R antagonist 1
Chemical Name: PAC1R antagonist 1
CAS Number: 2305204-24-2
Molecular Formula: C₁₇H₁₇ClN₆O₂
Molecular Weight: 372.81
Catalog: Research Areas Neurological Disease
Create Date: 2022-07-01 18:45:24
Modify Date: 2025-08-25 18:11:18
PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].

Name	PAC1R antagonist 1

Description	PAC1R antagonist 1 (compound 3d) is a potent and orally active antagonist of PAC1 receptor. PAC1R antagonist 1 can inhibit pituitary adenylate cyclase-activating polypeptide (PACAP)- and nerve injury-induced allodynia[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Takasaki I, et, al. Synthesis of a novel and potent small-molecule antagonist of PAC1 receptor for the treatment of neuropathic pain. Eur J Med Chem. 2020 Jan 15;186:111902.

Molecular Formula	C₁₇H₁₇ClN₆O₂
Molecular Weight	372.81