1784491-64-0

1784491-64-0 structure

Name: A2AAR antagonist 1
Chemical Name: A2AAR antagonist 1
CAS Number: 1784491-64-0
Molecular Formula: C₁₂H₈BrN₃O
Molecular Weight: 290.12
Catalog: Research Areas Neurological Disease
Create Date: 2022-10-24 19:11:30
Modify Date: 2025-08-24 19:36:14
A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].

Name	A2AAR antagonist 1

Description	A2AAR antagonist 1 (compound 21a) is an A2AAR (adenosine A2A receptor) antagonist with a Ki value of 20 nM. A2AAR antagonist 1 shows high ligand efficiency, and it can be used for the research of neurodegenerative diseases[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vitro	A2AAR antagonist 1 (0-10 μM; 1 h) shows a high affinity towards A2AAR with a Ki value of 20 nM[1].
References	[1]. Bolteau R, et al. High ligand efficiency quinazoline compounds as novel A2A adenosine receptor antagonists. Eur J Med Chem. 2022 Nov 5;241:114620.

Molecular Formula	C₁₂H₈BrN₃O
Molecular Weight	290.12