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2762423-09-4

2762423-09-4 structure

2762423-09-4 structure

Name: ERα antagonist 1
Chemical Name: ERα antagonist 1
CAS Number: 2762423-09-4
Molecular Formula: C₃₃H₃₂N₂O₅S
Molecular Weight: 568.68
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2022-07-11 06:10:49
Modify Date: 2025-08-25 22:03:13
ERα antagonist 1 (Compound 19d) is a potent, selective, covalent estrogen receptor α (ERα) antagonist. ERα antagonist 1 induces apoptosis and cell cycle G0/G1 phase arrest in MCF-7 cells[1].

Name	ERα antagonist 1

Description	ERα antagonist 1 (Compound 19d) is a potent, selective, covalent estrogen receptor α (ERα) antagonist. ERα antagonist 1 induces apoptosis and cell cycle G0/G1 phase arrest in MCF-7 cells[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
Target	ERα
References	[1]. Bai C, et al. Benzothiophene derivatives as selective estrogen receptor covalent antagonists: Design, synthesis and anti-ERα activities. Bioorg Med Chem. 2021 Oct 1;47:116395.

Molecular Formula	C₃₃H₃₂N₂O₅S
Molecular Weight	568.68

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