Calmodulin antagonist-1
Modify Date: 2025-08-27 05:34:40
Calmodulin antagonist-1 structure
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Common Name | Calmodulin antagonist-1 | ||
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| CAS Number | 78957-84-3 | Molecular Weight | 349.28 | |
| Density | N/A | Boiling Point | 501.5ºC at 760 mmHg | |
| Molecular Formula | C14H18Cl2N2O2S | Melting Point | 243-246ºC | |
| MSDS | N/A | Flash Point | 257.1ºC | |
Use of Calmodulin antagonist-1Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=375 μM) in a competitive fashion with respect to cyclic GMP and the Ki value is 300 μM[1]. |
| Name | N-(4-aminobutyl)-5-chloronaphthalene-1-sulfonamide,hydrochloride |
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| Synonym | More Synonyms |
| Description | Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=375 μM) in a competitive fashion with respect to cyclic GMP and the Ki value is 300 μM[1]. |
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| Related Catalog | |
| References |
| Boiling Point | 501.5ºC at 760 mmHg |
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| Melting Point | 243-246ºC |
| Molecular Formula | C14H18Cl2N2O2S |
| Molecular Weight | 349.28 |
| Flash Point | 257.1ºC |
| Exact Mass | 348.046600 |
| PSA | 80.57000 |
| LogP | 5.48440 |
| InChIKey | IKMXJMNRHREPOD-UHFFFAOYSA-N |
| SMILES | Cl.NCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12 |
| HS Code | 2935009090 |
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| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
| 1-Butanaminium, 4-[[(5-chloro-1-naphthalenyl)sulfonyl]amino]-, chloride (1:1) |
| N-(4-Aminobutyl)-5-chloronaphthalene-1-sulfonamide hydrochloride (1:1) |
| N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride |
| 4-{[(5-Chloro-1-naphthyl)sulfonyl]amino}-1-butanaminium chloride |
| N-(4-Aminobutyl)-5-chloro-1-naphthalenesulphonamide hydrochloride |
| OR0190T |
| Calmodulin antagonist-1 |