MCHr1 antagonist 1

Modify Date: 2024-01-16 14:04:35

MCHr1 antagonist 1 structure	Common Name	MCHr1 antagonist 1
	CAS Number	391610-37-0	Molecular Weight	557.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₃F₂N₅O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MCHr1 antagonist 1

MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.

Name	MCHr1 antagonist 1

Description	MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> MCHR1 (GPR24) Research Areas >> Metabolic Disease
Target	Kb: 1 nM (Human MCH1)[1] Ki: 4 nM (Human MCH1)[1]
In Vitro	MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].
References	[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1

Molecular Formula	C₂₈H₃₃F₂N₅O₅
Molecular Weight	557.59