1069622-60-1

1069622-60-1 structure
1069622-60-1 structure
  • Name: MCHR1 antagonist 3
  • Chemical Name: MCHR1 antagonist 3
  • CAS Number: 1069622-60-1
  • Molecular Formula: C29H36N4O2
  • Molecular Weight: 472.62
  • Catalog: Signaling Pathways GPCR/G Protein MCHR1 (GPR24)
  • Create Date: 2020-06-01 09:34:55
  • Modify Date: 2024-01-12 17:35:49
  • MCHR1 antagonist 3 is a potent the melanin-concentrating hormone receptor-1 (MCHR1) antagonist. MCHR1 antagonist 3 is used to regulate energy metabolism[1].

Name MCHR1 antagonist 3
Description MCHR1 antagonist 3 is a potent the melanin-concentrating hormone receptor-1 (MCHR1) antagonist. MCHR1 antagonist 3 is used to regulate energy metabolism[1].
Related Catalog
In Vitro Compound 1, derived from a spirohydantoin scaffold, exhibits a Ki of 50 nM at MCH-R1. Compound 1 is a potent inhibitor of CYP3A4 (IC50=35 nM). MCHR1 antagonist 3 is an analog of compound 1[1].
References

[1]. Rowbottom MW, et al. Synthesis and structure-activity relationships of spirohydantoin-derived small-moleculeantagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Bioorg Med Chem Lett. 2007 Apr 15;17(8):2171-8.

Molecular Formula C29H36N4O2
Molecular Weight 472.62