LIMK-IN-22j
Modify Date: 2025-08-25 23:52:12
LIMK-IN-22j structure
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Common Name | LIMK-IN-22j | ||
|---|---|---|---|---|
| CAS Number | 1116571-01-7 | Molecular Weight | 453.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H21BrN8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LIMK-IN-22jLIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1]. |
| Name | (2S)-N-(3-Bromophenyl)-N'-cyano-2-methyl-4-(5-methyl-7H-pyrrolo[2 ,3-d]pyrimidin-4-yl)-1-piperazinecarboximidamide |
|---|---|
| Synonym | More Synonyms |
| Description | LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK), with IC50s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research[1]. |
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| Related Catalog | |
| Target |
LIMK1:0.9 nM (IC50) LIMK2:0.5 nM (IC50) ROCK1:260 nM (IC50) ROCK2:2700 nM (IC50) |
| References |
| Molecular Formula | C20H21BrN8 |
|---|---|
| Molecular Weight | 453.34 |
| Exact Mass | 452.10700 |
| PSA | 96.23000 |
| LogP | 3.56438 |
| Hazard Codes | Xn |
|---|
|
~58%
LIMK-IN-22j CAS#:1116571-01-7 |
| Literature: US2009/42893 A1, ; Page/Page column 9; 10 ; US 20090042893 A1 |
![(S)-5-methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine structure](https://image.chemsrc.com/caspic/483/1116570-96-7.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| LIMK-IN-22j |