DC Chemicals Limited
China
Product Name: hDHODH-IN-1
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1173715-42-8

1173715-42-8 structure

1173715-42-8 structure

Name: hDHODH-IN-1
Chemical Name: hDHODH-IN-1
CAS Number: 1173715-42-8
Molecular Formula: C₁₇H₁₄N₂O₂
Molecular Weight: 278.31
Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
Create Date: 2020-04-09 12:04:16
Modify Date: 2024-02-04 22:01:28
hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].

Name	hDHODH-IN-1

Description	hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor. hDHODH-IN-1 has anti-inflammatory effect[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase Research Areas >> Inflammation/Immunology
In Vitro	Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase. Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers, multiple sclerosis, and autoimmune and inflammatory diseases[1].
References	[1]. Shih KC, et al. Development of a human dihydroorotate dehydrogenase (hDHODH) pharma-similarity index approach with scaffold-hopping strategy for the design of novel potential inhibitors. PLoS One. 2014 Feb 4;9(2):e87960.

Molecular Formula	C₁₇H₁₄N₂O₂
Molecular Weight	278.31