ROCK-IN-1

Modify Date: 2024-01-08 12:32:14

ROCK-IN-1 structure	Common Name	ROCK-IN-1
	CAS Number	934387-35-6	Molecular Weight	335.37
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₈FN₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ROCK-IN-1

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

Name	ROCK-IN-1

Description	ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK Research Areas >> Inflammation/Immunology Research Areas >> Cardiovascular Disease
Target	ROCK2:1.2 nM (IC50)
In Vitro	ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].
References	[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.

Molecular Formula	C₂₀H₁₈FN₃O
Molecular Weight	335.37

Hazard Codes	Xi