934387-35-6

934387-35-6 structure
934387-35-6 structure
  • Name: ROCK-IN-1
  • Chemical Name: ROCK-IN-1
  • CAS Number: 934387-35-6
  • Molecular Formula: C20H18FN3O
  • Molecular Weight: 335.37
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
  • Create Date: 2018-01-13 00:24:30
  • Modify Date: 2025-08-27 18:18:59
  • ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

Name ROCK-IN-1
Description ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.
Related Catalog
Target

ROCK2:1.2 nM (IC50)

In Vitro ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].
References

[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.

Molecular Formula C20H18FN3O
Molecular Weight 335.37
Hazard Codes Xi
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.