692870-25-0

692870-25-0 structure

Name: ROCK-IN-5
Chemical Name: WAY-658513
CAS Number: 692870-25-0
Molecular Formula: C₁₆H₁₁ClFN₃OS
Molecular Weight: 347.79
Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
Create Date: 2022-12-03 08:02:21
Modify Date: 2025-08-26 18:40:40
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research[1].

Name	WAY-658513
Synonyms	Benzeneacetamide, 2-chloro-6-fluoro-N-[4-(4-pyridinyl)-2-thiazolyl]- 2-(2-Chloro-6-fluorophenyl)-N-[4-(4-pyridinyl)-1,3-thiazol-2-yl]acetamide

Description	ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> GSK-3 Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> MAPK/ERK Pathway >> ERK Research Areas >> Neurological Disease Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3 Signaling Pathways >> TGF-beta/Smad >> ROCK Signaling Pathways >> Stem Cell/Wnt >> ERK
References	[1]. Jingrong Cao, et al. Compositions useful as inhibitors of rock and other protein kinases. WO2004041813A1.