DBCO-PEG1-amine

Modify Date: 2024-01-16 15:57:30

DBCO-PEG1-amine Structure
DBCO-PEG1-amine structure
Common Name DBCO-PEG1-amine
CAS Number 2364591-79-5 Molecular Weight 391.46
Density N/A Boiling Point N/A
Molecular Formula C23H25N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG1-amine


DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG1-amine

 DBCO-PEG1-amine Biological Activity

Description DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C23H25N3O3
Molecular Weight 391.46