2364591-77-3

2364591-77-3 structure

2364591-77-3 structure

Name: DBCO-PEG1-NH-Boc
Chemical Name: DBCO-PEG1-NH-Boc
CAS Number: 2364591-77-3
Molecular Formula: C₂₈H₃₃N₃O₅
Molecular Weight: 491.58
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-04 20:38:26
Modify Date: 2024-01-09 18:05:49
DBCO-PEG1-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG1-NH-Boc

Description	DBCO-PEG1-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₈H₃₃N₃O₅
Molecular Weight	491.58