Sulfo DBCO-amine

Modify Date: 2024-01-08 21:16:33

Sulfo DBCO-amine Structure
Sulfo DBCO-amine structure
Common Name Sulfo DBCO-amine
CAS Number 2028284-70-8 Molecular Weight 427.47
Density N/A Boiling Point N/A
Molecular Formula C21H21N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sulfo DBCO-amine


Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Sulfo DBCO-amine

 Sulfo DBCO-amine Biological Activity

Description Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C21H21N3O5S
Molecular Weight 427.47
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