Sulfo DBCO-PEG4-Maleimide

Modify Date: 2024-01-11 07:21:27

Sulfo DBCO-PEG4-Maleimide Structure
Sulfo DBCO-PEG4-Maleimide structure
Common Name Sulfo DBCO-PEG4-Maleimide
CAS Number 2055198-07-5 Molecular Weight 825.88
Density N/A Boiling Point N/A
Molecular Formula C39H47N5O13S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Sulfo DBCO-PEG4-Maleimide


Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Sulfo DBCO-PEG4-Maleimide
Synonym More Synonyms

 Sulfo DBCO-PEG4-Maleimide Biological Activity

Description Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C39H47N5O13S
Molecular Weight 825.88

 Synonyms

MFCD30458040
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