Shanghai Nianxing Industrial Co., Ltd
China
Product Name: N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
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Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2353409-72-8

2353409-72-8 structure

2353409-72-8 structure

Name: N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
Chemical Name: N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
CAS Number: 2353409-72-8
Molecular Formula: C₅₄H₇₄N₆O₁₆S
Molecular Weight: 1095.26
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 16:21:40
Modify Date: 2024-02-04 17:29:17
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS

Description	N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₅₄H₇₄N₆O₁₆S
Molecular Weight	1095.26

Hazard Codes	Xi