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2028284-70-8

2028284-70-8 structure
2028284-70-8 structure
  • Name: Sulfo DBCO-amine
  • Chemical Name: Sulfo DBCO-amine
  • CAS Number: 2028284-70-8
  • Molecular Formula: C21H21N3O5S
  • Molecular Weight: 427.47
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 11:18:52
  • Modify Date: 2024-01-08 21:16:33
  • Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Sulfo DBCO-amine
Description Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H21N3O5S
Molecular Weight 427.47