2364591-79-5

2364591-79-5 structure

2364591-79-5 structure

Name: DBCO-PEG1-amine
Chemical Name: DBCO-PEG1-amine
CAS Number: 2364591-79-5
Molecular Formula: C₂₃H₂₅N₃O₃
Molecular Weight: 391.46
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:13:20
Modify Date: 2024-01-16 15:57:30
DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG1-amine

Description	DBCO-PEG1-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₃H₂₅N₃O₃
Molecular Weight	391.46