1839049-33-0

1839049-33-0 structure

1839049-33-0 structure

Name: DBCO-C2-alcohol
Chemical Name: DBCO-PEG1
CAS Number: 1839049-33-0
Molecular Formula: C₂₁H₂₀N₂O₃
Molecular Weight: 348.40
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 13:52:16
Modify Date: 2024-01-21 23:48:01
DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	DBCO-PEG1
Synonyms	MFCD32207039

Description	DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₁H₂₀N₂O₃
Molecular Weight	348.40

Hazard Codes	Xi