t-Boc-Aminooxy-PEG1-amine

Modify Date: 2024-01-14 08:45:01

t-Boc-Aminooxy-PEG1-amine Structure
t-Boc-Aminooxy-PEG1-amine structure
Common Name t-Boc-Aminooxy-PEG1-amine
CAS Number 1844894-82-1 Molecular Weight 220.27
Density N/A Boiling Point N/A
Molecular Formula C9H20N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG1-amine


Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG1-C2-NH2
Synonym More Synonyms

 t-Boc-Aminooxy-PEG1-amine Biological Activity

Description Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H20N2O4
Molecular Weight 220.27

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD31561111