t-Boc-Aminooxy-PEG2-amine

Modify Date: 2024-01-09 19:37:07

t-Boc-Aminooxy-PEG2-amine Structure
t-Boc-Aminooxy-PEG2-amine structure
Common Name t-Boc-Aminooxy-PEG2-amine
CAS Number 252378-69-1 Molecular Weight 264.32
Density N/A Boiling Point N/A
Molecular Formula C11H24N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG2-amine


Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG2-C2-amine
Synonym More Synonyms

 t-Boc-Aminooxy-PEG2-amine Biological Activity

Description Boc-Aminooxy-PEG2-C2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H24N2O5
Molecular Weight 264.32

 Synonyms

MFCD29079399