2401831-99-8

2401831-99-8 structure
2401831-99-8 structure
  • Name: t-Boc-Aminooxy-PEG4-NHS ester
  • Chemical Name: t-Boc-Aminooxy-PEG4-NHS ester
  • CAS Number: 2401831-99-8
  • Molecular Formula: C20H34N2O11
  • Molecular Weight: 478.49
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:51:52
  • Modify Date: 2024-01-12 08:06:40
  • t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name t-Boc-Aminooxy-PEG4-NHS ester
Description t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H34N2O11
Molecular Weight 478.49