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t-Boc-Aminooxy-PEG1-amine

Names

[ CAS No. ]:
1844894-82-1

[ Name ]:
t-Boc-Aminooxy-PEG1-amine

[Synonym ]:
MFCD31561111

Biological Activity

[Description]:

Boc-Aminooxy-PEG1-C2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C9H20N2O4

[ Molecular Weight ]:
220.27

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds