Trk-IN-3
Modify Date: 2025-08-25 17:36:30
Trk-IN-3 structure
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Common Name | Trk-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 1873373-33-1 | Molecular Weight | 474.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H19F5N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Trk-IN-3Trk-IN-3 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1]. |
| Name | Trk-IN-3 |
|---|
| Description | Trk-IN-3 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 8.4 nM, 6.2 nM and 2.2 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1]. |
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| Related Catalog | |
| Target |
TrkA:8.4 nM (IC50, in cell-based assays) TrkB:6.2 nM (IC50, in cell-based assays) TrkC:2.2 nM (IC50, in cell-based assays) |
| In Vitro | Trk-IN-3 (Compound 19) also inhibits hERG in the FP and PX assay with IC50s of 79 μM and 88 μM, respectively[1]. |
| References |
| Molecular Formula | C20H19F5N4O4 |
|---|---|
| Molecular Weight | 474.38 |
| Hazard Codes | Xi |
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