Trk-IN-11

Modify Date: 2024-01-10 11:20:25

Trk-IN-11 structure	Common Name	Trk-IN-11
	CAS Number	2700265-62-7	Molecular Weight	411.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₂FN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trk-IN-11

Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK (IC50 = 1.4, 1.8 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key drug target in solid tumors. Trk-IN-11 has the potential for the research of cancer disease[1].

Name	Trk-IN-11

Description	Trk-IN-11 (Compound 14h) is a potent inhibitor of TRK (IC50 = 1.4, 1.8 nM, against TrkA, TrkAG595R, respectively). As a receptor tyrosine kinase (RTK), tropomyosin receptor kinase (Trk) is a key drug target in solid tumors. Trk-IN-11 has the potential for the research of cancer disease[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
References	[1]. Fan Y, et al. Pyrizolo[1,5-a]pyrimidine derivatives of the second-generation TRK inhibitor: Design, synthesis and biological evaluation. Bioorg Med Chem Lett. 2022;63:128646.

Molecular Formula	C₂₁H₂₂FN₅O₃
Molecular Weight	411.43

DC Chemicals Limited
China
Product Name: Trk-IN-11
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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