Trk-IN-9

Modify Date: 2024-01-22 18:24:43

Trk-IN-9 structure	Common Name	Trk-IN-9
	CAS Number	2758623-12-8	Molecular Weight	454.93
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₄ClFN₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trk-IN-9

Trk-IN-9 (Compound 12) is a potent inhibitor of TRK. Trk-IN-9 inhibits the proliferation of Km-12 cell lines. Trk-IN-9 induces the apoptosis of Km-12 cells in a concentration-dependent manner. Trk-IN-9 inhibits the phosphorylation of TRK to block downstream pathways. Trk-IN-9 has the potential for the research of NTRK-fusion cancers[1].

Name	Trk-IN-9

Description	Trk-IN-9 (Compound 12) is a potent inhibitor of TRK. Trk-IN-9 inhibits the proliferation of Km-12 cell lines. Trk-IN-9 induces the apoptosis of Km-12 cells in a concentration-dependent manner. Trk-IN-9 inhibits the phosphorylation of TRK to block downstream pathways. Trk-IN-9 has the potential for the research of NTRK-fusion cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Trk Receptor
References	[1]. Wu T, et al. Rational drug design to explore the structure-activity relationship (SAR) of TRK inhibitors with 2,4-diaminopyrimidine scaffold. Eur J Med Chem. 2022;230:114096.

Molecular Formula	C₂₃H₂₄ClFN₆O
Molecular Weight	454.93
Storage condition	-20°C

DC Chemicals Limited
China
Product Name: Trk-IN-9
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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