CCR2 antagonist 1
Modify Date: 2025-08-27 02:01:08
CCR2 antagonist 1 structure
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Common Name | CCR2 antagonist 1 | ||
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| CAS Number | 1683534-96-4 | Molecular Weight | 549.47 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H32BrF3N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CCR2 antagonist 1CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. |
| Name | CCR2 antagonist 1 |
|---|
| Description | CCR2 antagonist 1 is a high-affinity and long-residence-time CCR2 antagonist, with a Ki of 2.4 nM. |
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| Related Catalog | |
| Target |
CCR2:2.4 nM (Ki) |
| In Vitro | The combination of SAR and SKR in the hit-to-lead process results in the discovery of a new higheaffinity and longeresidenceetime CCR2 antagonist (CCR2 antagonist 1 (compound 15a), Ki=2.4 nM; RT=714 min)[1]. |
| References |
| Molecular Formula | C28H32BrF3N2O |
|---|---|
| Molecular Weight | 549.47 |
| InChIKey | QYDUEIJZRKTNKN-HYZYYIOASA-N |
| SMILES | CC(C)C1(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)CCC(NC2CCc3cc(Br)ccc32)C1 |