Cbz-NH-PEG1-CH2COOH

Modify Date: 2024-02-01 00:58:41

Cbz-NH-PEG1-CH2COOH structure	Common Name	Cbz-NH-PEG1-CH2COOH
	CAS Number	1260092-43-0	Molecular Weight	253.25100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₅NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cbz-NH-PEG1-CH2COOH

Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-(benzyloxycarbonylamino)ethoxy]acetic acid
Synonym	More Synonyms

Description	Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₂H₁₅NO₅
Molecular Weight	253.25100
Exact Mass	253.09500
PSA	84.86000
LogP	1.40490

z-o1pen-oh

5-(benzyloxycarbonyl-amino)-3-oxa-pentanoic acid