462100-05-6
462100-05-6 structure
- Name: Cbz-NH-PEG3-CH2COOH
- Chemical Name: 3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid
- CAS Number: 462100-05-6
- Molecular Formula: C16H23NO7
- Molecular Weight: 341.356
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-08-15 12:56:16
- Modify Date: 2024-04-05 14:56:26
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Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid |
|---|---|
| Synonyms |
2,7,10,13-Tetraoxa-4-azapentadecan-15-oic acid, 3-oxo-1-phenyl-
3-Oxo-1-phenyl-2,7,10,13-tetraoxa-4-azapentadecan-15-oic acid |
| Description | Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 534.1±50.0 °C at 760 mmHg |
| Molecular Formula | C16H23NO7 |
| Molecular Weight | 341.356 |
| Flash Point | 276.8±30.1 °C |
| Exact Mass | 341.147461 |
| PSA | 106.81000 |
| LogP | 0.44 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.519 |