1449390-66-2
1449390-66-2 structure
- Name: Cbz-NH-PEG5-CH2COOH
- Chemical Name: Z-NH-5(ethylene glycol)-acetic acid
- CAS Number: 1449390-66-2
- Molecular Formula: C20H31NO9
- Molecular Weight: 429.461
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-05 17:03:55
- Modify Date: 2024-01-14 11:51:59
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Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Z-NH-5(ethylene glycol)-acetic acid |
|---|---|
| Synonyms |
3-Oxo-1-phenyl-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
2,7,10,13,16,19-Hexaoxa-4-azaheneicosan-21-oic acid, 3-oxo-1-phenyl- |
| Description | Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 590.4±50.0 °C at 760 mmHg |
| Molecular Formula | C20H31NO9 |
| Molecular Weight | 429.461 |
| Flash Point | 310.9±30.1 °C |
| Exact Mass | 429.199890 |
| LogP | -0.27 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.508 |