1205751-19-4

1205751-19-4 structure

1205751-19-4 structure

Name: Cbz-NH-PEG1-CH2CH2COOH
Chemical Name: Cbz-NH-PEG1-CH2CH2COOH
CAS Number: 1205751-19-4
Molecular Formula: C₁₃H₁₇NO₅
Molecular Weight: 267.28
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:16:34
Modify Date: 2024-01-10 11:16:31
Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Cbz-NH-PEG1-CH2CH2COOH
Synonyms	MFCD14582436

Description	Cbz-NH-PEG1-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₁₃H₁₇NO₅
Molecular Weight	267.28

Hazard Codes	Xi