LPA2 antagonist 1
Modify Date: 2024-01-08 14:25:11
LPA2 antagonist 1 structure
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Common Name | LPA2 antagonist 1 | ||
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| CAS Number | 1017606-66-4 | Molecular Weight | 500.465 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 684.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C20H23Cl2N5O2S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 367.8±34.3 °C | |
Use of LPA2 antagonist 1LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM. |
| Name | N-[(2S)-1-{4-[(3,4-Dichlorophenyl)sulfonyl]-1-piperazinyl}-2-propanyl]-7-methylthieno[3,2-d]pyrimidin-4-amine |
|---|---|
| Synonym | More Synonyms |
| Description | LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM. |
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| Related Catalog | |
| Target |
IC50: 17 nM (LPA2)[1] |
| In Vitro | LPA2 antagonist 1 inhibits the phosphorylation of Erk induced by LPA in a concentration dependent manner. LPA2 antagonist 1 inhibits HCT-116 colon cancer cell proliferation caused by LPA in a doses dependent manner[1]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 684.6±65.0 °C at 760 mmHg |
| Molecular Formula | C20H23Cl2N5O2S2 |
| Molecular Weight | 500.465 |
| Flash Point | 367.8±34.3 °C |
| Exact Mass | 499.067017 |
| PSA | 115.05000 |
| LogP | 6.48 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.663 |
| Storage condition | 2-8℃ |
| N-[(2S)-1-{4-[(3,4-Dichlorophenyl)sulfonyl]-1-piperazinyl}-2-propanyl]-7-methylthieno[3,2-d]pyrimidin-4-amine |
| N-[(2S)-1-{4-[(3,4-dichlorophenyl)sulfonyl]piperazin-1-yl}propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine |
| thieno[3,2-d]pyrimidin-4-amine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-methylethyl]-7-methyl- |
| LPA2 antagonist 1 |