LPA2 antagonist 2

Modify Date: 2024-01-10 13:23:25

LPA2 antagonist 2 Structure
LPA2 antagonist 2 structure
Common Name LPA2 antagonist 2
CAS Number 36840-10-5 Molecular Weight 380.35100
Density 1.444±0.06 g/cm3(Predicted) Boiling Point 758.0±60.0 °C(Predicted)
Molecular Formula C20H16N2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LPA2 antagonist 2


LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM, which is >480-fold more selective than LPA3 (IC50 of 13.85 μM)[1].

 Names

Name 4,4'-(4,4'-Biphenyldiyldiimino)Bis(4-Oxo-2-Butenoic Acid)
Synonym More Synonyms

 LPA2 antagonist 2 Biological Activity

Description LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM, which is >480-fold more selective than LPA3 (IC50 of 13.85 μM)[1].
Related Catalog
Target

IC50: 28.3 nM (LPA2); 13.85 μM (LPA3)[1]

References

[1]. Fells JI, et al. Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem. 2008 Jun 1;16(11):6207-17.

 Chemical & Physical Properties

Density 1.444±0.06 g/cm3(Predicted)
Boiling Point 758.0±60.0 °C(Predicted)
Molecular Formula C20H16N2O6
Molecular Weight 380.35100
Exact Mass 380.10100
PSA 132.80000
LogP 2.65820
Storage condition 2-8°C

 Synonyms

MFCD00566434
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