LPA2 antagonist 2

Names

[ Name ]:
LPA2 antagonist 2

[Synonym ]:
MFCD00566434

Biological Activity

[Description]:

LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM, which is ＞480-fold more selective than LPA3 (IC50 of 13.85 μM)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> LPL Receptor

[Target]

IC50: 28.3 nM (LPA2); 13.85 μM (LPA3)[1]

[References]

[1]. Fells JI, et al. Identification of non-lipid LPA3 antagonists by virtual screening. Bioorg Med Chem. 2008 Jun 1;16(11):6207-17.

Chemical & Physical Properties

[ Density]:
1.444±0.06 g/cm3(Predicted)

[ Boiling Point ]:
758.0±60.0 °C(Predicted)

[ Molecular Formula ]:
C₂₀H₁₆N₂O₆

[ Molecular Weight ]:
380.35100

[ Exact Mass ]:
380.10100

[ PSA ]:
132.80000

[ LogP ]:
2.65820

[ Storage condition ]:
2-8°C

Related Compounds

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