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CXCR2 antagonist 2

Names

[ CAS No. ]:
2647464-91-1

[ Name ]:
CXCR2 antagonist 2

Biological Activity

[Description]:

CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy with an IC50 value of 95 nM.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> CXCR
Signaling Pathways >> Immunology/Inflammation >> CXCR

[References]

[1]. Dong Y, et al. Discovery of Benzocyclic Sulfone Derivatives as Potent CXCR2 Antagonists for Cancer Immunotherapy. J Med Chem. 2021 Nov 25;64(22):16626-16640.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H17FN2O4S

[ Molecular Weight ]:
364.39

Related Compounds